RiskGLOBAL

Overview

RiskGLOBAL is our test that check for 45 gene mutations related to hereditary Breast, Colorectal, Duodenal, Gastrointestinal, Genitourinary, Leukemias, Ovarian, Melanoma, Pancreatic, Prostate, Thyroid, Sarcoma, Small Intestine, Stomach and Uterus Cancer.

Thanks that, RiskGLOBAL is the more complete test for high-risk men and women, including those with a family history of all cancers mentioned above.

 

Click here to download the brochure in PDF format.

RiskGLOBAL Basis

RiskGLOBAL captures and direct sequences all the genomic regions for 45 genes, using modern Next Generation Sequencing (NGS) techniques in combination with more classical approaches of molecular genetics.

Through RiskGLOBAL, it is possible to detect point mutations in exons, deep intronic regions (up to 45bb) and in untranslated regulatory regions of the genes, as well as some structural variants.

The whole list of genes that RiskGLOBAL check is:

  • APC, ATM, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, EPCAM, FH, FLCN, MAX, MEN1, MET, MITF, MLH1, MRE11A, MSH2, MSH6, MUTYH, NBN, NF1, PALB2, PMS2, POLD1, POLE, PTEN, RAD50, RAD51C, RAD51D, RET, SDHAF2, SDHB, SDHC, SDHD, SMAD4, STK11, TMEM127, TP53, TSC1, TSC2 and VHL.

Indications for use for RiskGLOBAL

RiskGLOBAL is indicated to detect 45 gene mutations related to hereditary Breast, Colorectal, Duodenal, Gastrointestinal, Genitourinary, Leukemias, Ovarian, Melanoma, Pancreatic, Prostate, Thyroid, Sarcoma, Small Intestine, Stomach and Uterus Cancer for complete study.

Moreover, unlike BIOPROGNOS’ tests to help in diagnosis (such as OncoBREAST Dx, OncoLUNG Dx, OncoOVARIAN Dx, OncoPROSTATE Dx or OncoCUP Dx), RiskGLOBAL does not need a receipt or prescription.

How to get tested

Once the purchase process is completed through this web page, you will receive a Saliva Kit at your home to take a sample of your saliva.

 

 

Once you receive our Saliva Kit, please just follow the instructions included and send us again with already postage paid.

After about 20 business days (depending on your location), RiskGLOBAL results will be sent by email to the email provided during the purchase process.

References

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